Research progress of magnetic resonance imaging contrast agents |
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Authors: | Guoping Yan Renxi Zhuo |
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Affiliation: | (1)Laboratory of Biomedical Polymer Materials of the Ministry of Education of China, Department of Chemistry, Wuhan University, Wuhan 430072 ,China |
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Abstract: | Magnetic resonance imaging (MRI) is a clinical diagnostic modality, which has become popular in hospitals around the world. Approximately 30% of MRI exams include the use of contrast agents. The research progress of the paramagnetic resonance imaging contrast agents was described briefly. Three important approaches in the soluble paramagnetic resonance imaging contrast agents design including nonionic, tissue-specific and macromolecular contrast agents were investigated. In addition, the problems in the research and development in future were discussed. |
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Keywords: | magnetic resonance imaging (MRI) contrast agents gadolinium(m) complexes tissue-specific. |
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