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Interaction between the soluble and particulate neuraminidases of chick liver
Authors:D. R. P. Tulsiani  V. P. Bhavanandan  R. Carubelli
Affiliation:(1) Biomembrane Research Laboratory, Oklahoma Medical Research Foundation, 825 Northeast 13th Street, 73104 Oklahoma City, Oklahoma, USA;(2) Present address: Department of Molecular Biology, Vanderbilt University, 37232 Nashville, Tennessee, USA;(3) Present address: Department of Biological Chemistry, The Milton S. Hershey Medical Center, The Pennsylvania State University, 17033 Hershey, Pennsylvania, USA
Abstract:Summary The sum of the neuraminidase activities found in the isolated soluble and particulate fractions of chick liver was considerably higher than that observed in the cytoplasmic extract from which these fractions were obtained. Addition of increasing amounts of particulate neuraminidase to a constant amount of the soluble preparation resulted in a progressive loss of enzyme activity.This investigation was supported in part by U. S. Public Health Service Grant NS09176 from the National Institutes of Health.
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