三[（5-亚甲基-8-羟基喹啉）氨基乙基]胺及其稀土配合物的合成、表征和与DNA的作用

为研究三爪结构配体稀土配合物的组成、可能的配位状态及与DNA的作用方式,合成了新型三爪结构配体——三[（5-亚甲基-8-羟基喹啉）氨基乙基]胺及其5种稀土配合物.用元素分析、摩尔电导率、IR光谱和TG-DTA方法分析了该类化合物的组成和结构;通过UV光谱和荧光光谱研究了配合物与CT DNA的作用方式.结果表明,该系列配合物的组成为[REL（NO3）2]NO3.4 H2O（RE=Eu,Tb,Nd,La,Ce）,其中2个硝酸根以双齿形式与金属离子配位,总配位数为10;配合物与CT DNA之间存在着插入作用.

Synthesis,Characterization and Properties of Rare Earth Complexes with Tris[(5-methylene-8-hyddroxyquinoline)amino-ethyl]Amine Base

To study the composition,compared probable coordination structure and intercalation of tripodal and their rare earth complexes,a new tripodal ligand and its five complexes with rare earth metals are synthesized.The complexes were characterized by elemental analysis,IR,molar conductivity,TG-DTA and molar conductance measurements.The results show that these complexes [REL（NO3）2]NO3·nH2O（n=4,RE= Eu^3＋,Tb^3＋,Nd^3＋,La^3＋,Ce^3＋） are 1∶1,where one nitrate radical is free,the other two nitrate radicals are in di-dentate coordination with rare earth ions;the coordination number is 10.The interaction between the complex and ct-DNA has been studied by electronic absorption spectroscopy,fluorescence,and the viscosity measurement.All of the results indicate that the interaction of the complex with CT DNA is intercalation.