Scanning electron microscopy of antibody-dependent cell-mediated cytotoxicity of Friend leukemia virus-infected spleen cells |
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| Authors: | P A Farber H Friedman |
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| Institution: | (1) Department of Pathology, Temple University School of Dentistry, 19140 Philadelphia, Pennsylvania, USA;(2) Present address: Dept. of Microbiology, University of South Florida College of Medicine, Tampa, Florida, USA |
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| Abstract: | Summary Friend leukemia virus (FLV) infected splenocytes treated with rabbit anti-FLV serum and subsequently incubated with splenic lymphocytes from non-immune Balb/c mice were examined by scanning electron microscopy. Villous-covered lymphocytes adherred to the tumor cells and induced surface blebs, numerous membrane pores and eventual tumor cell lysis. |
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