Experimental hydrocephalus following mechanical increment of intraventricular pulse pressure |
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| Authors: | C. Di Rocco V. E. Pettorossi M. Caldarelli R. Mancinelli F. Velardi |
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| Affiliation: | (1) Istituti di Fisiologia Umana e di Neurochirurgia, Università Cattolica S. Cuore, via della Pineta Sacchetti, 644, I-00168 Roma, Italy;(2) Present address: Istituto di Fisiologia Umana, Università Cattolica S. Cuore, via della Pineta Sacchetti 644, I-00168 Roma |
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| Abstract: | Summary Experimental hydrocephalus has been induced in lambs by artificial increase of the amplitude of intraventricular cerebrospinal fluid (CSF) oscillations related to arterial pulsations, without concominant changes of the mean CSF-pressure. The characteristics of this hydrocephalus demonstrate that the intraventricular CSF-pulsations can play a role in the genesis of ventricular dilatation. Such a method may be used to produce an original model of hydrocephalus independent of changes of CSF-circulation or absorption.This work was supported by grant of CNR. |
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