Brain glycogen following experimental cerebral ischemia in gerbils (Meriones unguiculatus) |
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| Authors: | B B Mrsulja W D Lust B J Mrsulja J V Passonneau I Klatzo |
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| Institution: | (1) Laboratory of Neuropathology and Neuroanatomical Sciences National Institute of Neurological and Communicative Disorders and Stroke, National Institutes of Health, Building 36, Room 4D08, 20014 Bethesda, Maryland, USA |
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| Abstract: | Summary Cortical glycogen levels decreased after both 1 and 3 h of unilateral ischemia. After 1 h of recirculation, the levels of glycogen were restored to control values in both groups. Subsequently, glycogen increased above normal levels after 1 week of recirculation in the 1 h ischemic groups, and after 5 h in the 3 h ischemic group. Thus, the onset of the excess glycogen accumulation appears to be dependent on the intensity of the ischemic insult. |
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