Red blood cell glutathione peroxidase in simple trisomy 21 and translocation 21/22 |
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Authors: | J. Kedziora R. Lukaszewicz M. Koter G. Bartosz B. Pawłowska D. Aitkin |
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Affiliation: | (1) Department of Physiology, WAM Medical Academy, Pl.9 Maja No. 1, PL-90-647 Łódż, (Poland);(2) Present address: Department of Biophysics, University of Łódź, Łódź, (Poland);(3) Present address: Department of Medical Genetics, Royal Hospital for Sick Children, York Hill, Glasgow, (Scotland) |
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Abstract: | Summary Red blood cell glutathione peroxidase activity was increased by bbout 50% in all Down's syndrome patients studied. It was slightly lower in translocation as compared with simple trisomy 21 but much higher with respect to controls. We are indebted to Prof. M. Ferguson-Smith from the Department of Medical Genetics, Royal Hospital for Sick Children, Glasgow, Scotland, for helpful discussions regarding our results. |
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