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归胃经寒性中药对胃热证大鼠体征的影响
引用本文:黄雪群,李小梅,李续娥.归胃经寒性中药对胃热证大鼠体征的影响[J].华南师范大学学报(自然科学版),2010,1(1):18-18.
作者姓名:黄雪群  李小梅  李续娥
作者单位:1.1.华南师范大学生命科学学院2.华南师范大学
基金项目:广东省自然科学基金资助项目(7005844)
摘    要:用干姜水煎剂连续灌胃大鼠15d,复制胃热证大鼠模型,再分别以黄连、蒲公英、枳实水煎剂灌胃治疗10d。比较大鼠的饮食量、大小便、舌色舌苔变化,用放射免疫分析法测定大鼠血清中白细胞介素-4(IL-4)、白细胞介素-8(IL-8)的浓度变化。结果显示,造模后大鼠呈现舌红苔黄(P0.05)、饮食量增加(10%以上)、大小便量减少(10%以上)、且大便多数干结、小便颜色加深(P0 .01)、IL-8显著升高(P0.01)。黄连、蒲公英、枳实可改善上述胃热证的指标,且寒性程度愈高、治疗效果愈好。经分析得知,黄连、蒲公英、枳实通过降低胃热证大鼠血清中的IL-8,改善胃热证大鼠的体征。

关 键 词:黄连    蒲公英    枳实    胃热证    体征
收稿时间:2009-07-31

INFLUENCES OF COLD CHINESE HERBAL MEDICINE WITH STOMACH-MERIDIAN TROPISM N GENERAL SYMPTOM OF RATS WITH STOMACH-HEAT SYNDROME
HUANG Xuequn,LI Xiaomei,LI Xu'e.INFLUENCES OF COLD CHINESE HERBAL MEDICINE WITH STOMACH-MERIDIAN TROPISM N GENERAL SYMPTOM OF RATS WITH STOMACH-HEAT SYNDROME[J].Journal of South China Normal University(Natural Science Edition),2010,1(1):18-18.
Authors:HUANG Xuequn  LI Xiaomei  LI Xu'e
Institution:1. Guangdong Key Lab of Biotechnology for Plant Development;South China Normal University;Guangzhou 510631;China;2. Qingyuan Polytechnic College;Qingyuan;Guangdong 511510;3. School of Life Science;Guangzhou University;Guangzhou 510511;China
Abstract:Rats were fed with decoction of Rhizoma zingiberis for 15 days to induce the model of stomach-heat syndrome. After modeling, the decoctions of Rhizoma Coptidis (RC), Herba Taraxaci (HT) and Fructus Aurantii Immaturus (FAI) were given respectively to corresponding groups for 10 days. After the treatment, the amount of the daily diet, volume and absorbance of urine, pellet number and moistness of excrement, color and coating degree of tongue were recorded, the contents of interleukin-4 (IL-4) and interleukin-...
Keywords:Rhizoma Coptidis  Herba Taraxaci  Fructus Aurantii Immaturus  stomach-heat syndrome  general symptom  
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