中华眼镜蛇毒灌胃后的兔血清对人肺腺癌细胞株的影响

目的：了解中华眼镜蛇毒灌胃后的兔血清对人肺腺癌细胞的影响。方法：采用体外细胞培养的方法，观察蛇毒灌胃后的兔血清对人肺腺癌细胞及人胚肺成纤维细胞的细胞毒作用，对细胞生长及分裂数的影响。结果：蛇毒灌胃后的兔血清能够明显抑制肺腺癌细胞的生长，且其抑制效应随剂量的增加而增加，但该血清对正常人胚肺成纤维细胞的生长却没有明显影响。结论：中华眼镜蛇毒灌胃后的兔血清对肺腺癌细胞的生长有明显的抑制作用，且有高度的选择性。

Effect of serum preparation derived from rabbits after the gastrolavage with Naja naja atra venom on human lung adenocarcioma cell line

Aim: To study the effect of serum preparation derived from rabbits after the gastrolavage with Naja naja atra venom on human lung adenocarcinoma cell line. Methods: Using the method of culturing out-body cells, we observed the change of cytotoxicity, living curve and cells division of human lung adenocarcinoma cell line and human fetal lung fibroblast after added the serum of Naja naja atra venom.Results: The serum of Naja naja atra venom can obviously inhibits the growth of human lung adenocarcinoma cells and its inhibitive effects increase when the dosage increases, whereas the serum can not inhibit the growth of the human fetal lung fibroblast. Conclusion:The serum preparation derived from rabbits after the gastrolavage with Naja naja atra venom inhibited the growth of human lung adenocarcinoma cell line, which is high selectivity.