A possible genetic component of obesity in childhood. Observations on acid phosphatase polymorphism |
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| Authors: | N Lucarini G Finocchi F Gloria-Bottini M Macioce P Borgiani A Amante E Bottini |
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| Institution: | Chair of Human Development, 2nd University of Rome School of Medicine, Italy. |
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| Abstract: | Phenotypes of acid phosphatase with low enzymatic activity (ACP1 A and BA) are correlated with the highest degree of body mass increase observed in a sample of obese children. Since acid phosphatase probably functions as a flavin-mononucleotide phosphatase, differential modulation of flavo-enzyme activity and energy metabolism due to acid phosphatase genetic variability may explain the observed association. |
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