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Effect of prolactin on human red cell sodium transport |
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| Authors: | V Gopalakrishnan S Ramaswamy N P Pillai S Ranganathan M N Ghosh |
| Abstract: | Incubation of red cells with higher concentrations of prolactin in vitro enhanced the cellular sodium level and produced a significant reduction in erythrocyte membrane adenosine triphosphatase activity. This effect was dose and time-dependent. It is the result of an inhibition of the active sodium pump similar to that produced by ouabain, suggesting altered red cell function and electrolyte balance in hyperprolactinemic states. |
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