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依那普利对高血压病患者左心功能及血浆心钠素水平的影响
引用本文:单光华,陈玉琼,李昌棣.依那普利对高血压病患者左心功能及血浆心钠素水平的影响[J].暨南大学学报,1996(4).
作者姓名:单光华  陈玉琼  李昌棣
作者单位:暨南大学医学院附属医院急诊科
摘    要:采用放免法及多普勒超声测定34例Ⅰ~Ⅱ期高血压病患者及20例正常人血浆心钠素水平(PANFC)及左心功能,并给高血压病人Enalapril治疗2周,观测它对血浆心钠素水平和左心功能的影响。结果发现。高血压病人PANFC显著升高(P<0.05),左心功能受损害,Enalapril能明显降压,同时降低血浆心钠素水平,改善左心功能,增加心排血量

关 键 词:高血压  心功能  心钠素  依那普利

Effect of Enalapril on Cardiac Function and Plasma Concentration of Atrial Natriuretic Factor in Patients with Essential Hypertention
Shan Guanghua,Chen Yuqiong,Li Changdi.Effect of Enalapril on Cardiac Function and Plasma Concentration of Atrial Natriuretic Factor in Patients with Essential Hypertention[J].Journal of Jinan University(Natural Science & Medicine Edition),1996(4).
Authors:Shan Guanghua  Chen Yuqiong  Li Changdi
Institution:Shan Guanghua 1) Chen Yuqiong 2) Li Changdi 2)
Abstract:The present study was undertaken to determine the effects of Enalapril on the cardiac function and plasma concentration of atrial natriuretic factor (PANFC). Thirty-four cases with essential hypertension and twenty normotensive controls were investigated. The left ventricular function and PANFC were measured by pulse Doppler Echocardiography and radioimmunoassay respectively. All measurements were taken be-fore and after two-week-Enalapril treatment. The results indicate that: patients with essential hypertension are probably complicated with left ventricular dysfunction; The plasma natriuretic factor level is higher in patients wiiht essential hypertension; Treatment with Enalapril reduces MAP,PANFC in parallel with left ventricular function improvement.
Keywords:hypertension  atrial natriuretic factor  cardiac function  Enalapril
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