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A new semisynthetic ergot peptide alkaloid: DCN 203-922 |
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| Authors: | R K Giger H R Loosli M D Walkinshaw B J Clark J M Vigouret |
| Institution: | Preclinical Research, Sandoz Ltd., Basel, Switzerland. |
| Abstract: | We report the synthesis, stereochemistry and preliminary pharmacological evaluation of DCN 203-922, a novel ergot alkaloid of the cyclol type, which contains in its peptide moiety the uncommon amino acid L-allo-isoleucine. |
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