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Tumor incidence in Visna virus inoculated mice
Authors:E Lycke  B Svennerholm
Institution:(1) Department of Virology, Institute of Medical Microbiology, Sahlgrenska Sjukhuset, S-413 45 Göteborg, (Sweden)
Abstract:Summary Mice (female Swiss albino) inoculated when newborn with Visna virus had tumors in 77% of cases when examined 8–12 months later. The tumors were mainly of the mammary carcinoma type. The tumor incidence in noninfected control animals was only 20%. In contrast, no increased incidence of tumors was observed among Visna virus-inoculated inbred mice (BALB/c, CBA and DBA) with low incidence of spontaneous mammary carcinoma.This study was supported by grant No. B75-16X-4511-01 of the Swedish Medical Research Council.
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