Goldfish β-catenin cell-autonomously inhibits the expression of early neural development regulating gene vsx1 |
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基金项目: | supported by the National Natural Science Foundation of China (Grant No. 30430370);;National Key Basic Research and Devel-opment Program of China (Grant No. 2004CB117401) |
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摘 要: | β-catenin gene is essential for the formation of normal dorsal axial structure in vertebrates. Recent studies have provided evidence that β-catenin has a certain role in restricting the amount of organizer-induced neurectoderm formation in zebrafish and Xenopus laevis. To further understand how β-catenin represses the induction of neurectoderm formation and whether the inhibition of neural progenitor fates is essential for the normal organizer formation, it was investigated whether β-catenin was involved in...
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关 键 词: | β-catenin vsx1 boz chordamesoderm development |
收稿时间: | 2009-05-18 |
修稿时间: | 2009-07-13 |
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