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HMBA诱导红白血病细胞分化作用的研究
引用本文:王艾琳,李坚,许卫东.HMBA诱导红白血病细胞分化作用的研究[J].北华大学学报(自然科学版),2003,4(4):314-315.
作者姓名:王艾琳  李坚  许卫东
作者单位:1. 北华大学,医学院,吉林,吉林,132001
2. 吉林省地方病防治二所,吉林,吉林,132001
摘    要:目的:研究HMBA对红白血病细胞的抑制及诱导分化作用.方法:绘制HMBA作用下的红白血病细胞生长曲线,计数其分裂指数,联苯胺染色法检测其分化百分率.结果:红白血病细胞在HMBA作用下增殖能力下降,分裂指数减低,联苯胺染色阳性率为76%.结论:HMBA能抑制红白血病细胞生长繁殖并可诱导其分化.

关 键 词:HMBA  红白血病细胞  分化
文章编号:1009-4822(2003)04-0314-02
修稿时间:2003年4月1日

Study on HMBA Induced Differentiation of Eryoleukemia Cell
WANG Ai-lin LI Jian,XU Wei-dong.Study on HMBA Induced Differentiation of Eryoleukemia Cell[J].Journal of Beihua University(Natural Science),2003,4(4):314-315.
Authors:WANG Ai-lin LI Jian  XU Wei-dong
Abstract:Objective To study the effect of HMBA on inhibition and differentiation of eryoleukemia cell. Methods To make the growth curve of eryoleukemia cell, count eryoleukemia cell mitosis index and benzidine staining positive percentage when the eryoleukemia cell were exposed to HMBA. Results The numbers of eryoleukemia cell exposed HMBA to reduce, mitosis index decrease. Benzidine staining positive percentage is 76% . Conclusion HMBA can inhibit eryoleukemia cell proliferation and induce differentiation.
Keywords:HMBA  Eryroleukemia cell  Differentiation
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