Blood pressure and impairment of endothelium-dependent relaxation in spontaneously hypertensive rats |
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| Authors: | S Sunano S Osugi K Shimamura |
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| Institution: | Research Institute of Hypertension, Kinki University, Osaka, Japan. |
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| Abstract: | Correlation between hypertension and impairment of endothelium-dependent relaxation was demonstrated using aortae from certain strains of rats with various levels of spontaneous hypertension. It was also observed that the impairment of endothelium-dependent relaxation is the secondary change due to hypertension, and the level and duration of hypertension is the determinant factor of the impairment. |
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