Cortisone sensitive T-cells in Peyer's patches |
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Authors: | Rosy Eloy Dominique Vuitton J. -P. Vaultier Michèle Klein J. F. Grenier |
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Affiliation: | (1) Unit of Surgical Research and Biophysiopathology of the Intestine, Unité 61 INSERM, Avenue Molière, F-67200 Strasbourg-Hautepierre, France |
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Abstract: | Summary Pretreatment of donor lymphoid cells with cortisone has been shown to depress the T-cell subpopulation responsible for cellular proliferation in the GVH reaction. A quantitative assay as well as the histological criteria of the GVH reaction have been used in this study to demonstrate the presence of cortisone-sensitive T-cells within the Peyer's patches as well as in the spleen and mesenteric lymph nodes in the rat.This work was supported by a grant of the Délégation Générale à la Recherche Scientifique et Technique (No. 74-7-0619). |
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