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Reduction of acute toxicity of cyclophosphamide and X-rays by the new immunomodulating compound BM 12.531. |
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| Authors: | U Bicker K D Friedberg G Hebold K Mengel |
| Abstract: | BM 12.531, the 2-[2-cyanaziridinyl-(1)]-2-[2-carbamoylaziridinyl-(1)]-propane, (prop. INN Azimexon), reduces significantly the acute toxicity of cyclophosphamide and X-rays in rats and mice, respectively. The leucopenia induced by X-rays was partially compensated by BM 12.531 in rats. |
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