| 免疫机制在心肌炎发生、发展中的作用 |
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| 引用本文： | 李颖,石瑛. 免疫机制在心肌炎发生、发展中的作用[J]. 北华大学学报(自然科学版), 2003, 4(4): 292-295 |
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| 作者姓名： | 李颖 石瑛 |
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| 作者单位： | 1. 北华大学,附属医院,吉林,吉林,132011
2. 北华大学,医学院,吉林,吉林,132001 |
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| 基金项目： | 吉林省教育厅科研基金(吉教合字9851) |
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| 摘 要： | 免疫机制在心肌炎发病机制中有着重要的作用．心肌炎发病时，外周血中淋巴细胞及其亚群发生明显改变，外周血淋巴细胞活化标志的表达亦呈现规律性变化，急性期既有T细胞免疫功能活性增加，也有B细胞免疫功能活性增加，而随着病人的康复，免疫功能活性则下降．心肌炎发病时细胞因子的平衡受损主要表现为细胞因子IL-1，IL-6和TNF-α，IL-2和干扰素-γ(IFN-γ)水平升高．可考虑将免疫调节制剂用于该疾病的治疗。
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| 关 键 词： | 免疫机制 心肌炎 细胞因子 |
| 文章编号： | 1009-4822(2003)04-0292-04 |
| 修稿时间： | 2002-12-20 |
The Function of Immune Mechanism in the Occuring and Developing Myocarditis |
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| LI Ying,SHI Ying. The Function of Immune Mechanism in the Occuring and Developing Myocarditis[J]. Journal of Beihua University(Natural Science), 2003, 4(4): 292-295 |
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| Authors: | LI Ying SHI Ying |
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| Abstract: | Immune mechanism is very important to develop myocarditis. Peripheral blood mononuclear celis (PBMC) and its sub-population will be apparently changed during the myocarditis, and their markers will be regularly varied, too. In the acutephase, activation of T and B lymphocytes are up-modulation. Following the patients recovering from illness, activation of immunity will be down-modulation. As the same titne, the balance of cytokins is damaged. For example, the Ievel of IL-1, IL-6, IFN-7, IFN-a and IL-2 will become higher. The immune regulator will be implied clinical treatment. |
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| Keywords: | Immune mechanism Myocarditis Cytokin |
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