Depletion of synaptic vesicles at the frog (Rana pipiens) neuromuscular junctions by tetraphenylboron |
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| Authors: | Dr I G Marshall R L Parsons W K Paull |
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| Institution: | (1) Department of Physiology and Biophysics and Department of Anatomy, College of Medicine, University of Vermont, 05401 Burlington, Vermont, USA;(2) Present address: Department of Physiology and Pharmacology, University of Strathclyde, G1 1XW Glasgow, Scotland |
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| Abstract: | Summary At the frog neuromuscular junction tetraphenylboron produced a decrease in miniature endplate potential amplitude, accompanied by a decrease in the number but not the size of synaptic vesicles.This work was supported by NIH Grants Nos NS-07740 and NS-05707 to R. L. P. and was done during the tenure of a Research Fellowship of Muscular Dystrophy Associations of America, a Wellcome Research Travel Grant and a grant from the Carnegie Trust for the Universities of Scotland to I. G. M. The assistance of Dr.R. M. Schnitzler, W. G. Boldosser andP. M. Spannbauer is gratefully acknowledged. |
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