| 7种席夫碱对Zn2+的现场配位吸收光谱和99mTc现场配位法标记 |
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| 引用本文： | 王明召,宁亚兰,孟昭兴,刘伯里.7种席夫碱对Zn2+的现场配位吸收光谱和99mTc现场配位法标记[J].北京师范大学学报(自然科学版),2003,39(6):790-795. |
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| 作者姓名： | 王明召 宁亚兰 孟昭兴 刘伯里 |
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| 作者单位： | 北京师范大学化学系,100875,北京 |
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| 基金项目： | 国家自然科学基金;29731020; |
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| 摘 要： | 通过电子吸收光谱研究了7种水杨醛氨基酸席夫碱配体与Zn^2 离子在水溶液中现场配位的浓度下限、pH下限和配合的物稳定存在时间．初步探索了在生理盐水中7种水杨醛氨基酸席夫碱的^99mTc现场标记．实验结果初步揭示出现场配位法具有标记放射性金属核素的潜力．
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| 关 键 词： | 水杨醛氨基酸席夫碱 Zn^2＋ 现场配位 ^99mTc标记 |
| 修稿时间： | 2003年6月16日 |
ABSORPTIVE SPECTRAL STUDY ON COMPLEXING Zn2+ AND STUDY ON 99mTc LABELING OF THE IN SITU COORDINATION OF SEVEN SCHIFF BASES |
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| Wang Mingzhao,Ning Yalan,Meng Zhaoxing,Liu Boli.ABSORPTIVE SPECTRAL STUDY ON COMPLEXING Zn2+ AND STUDY ON 99mTc LABELING OF THE IN SITU COORDINATION OF SEVEN SCHIFF BASES[J].Journal of Beijing Normal University(Natural Science),2003,39(6):790-795. |
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| Authors: | Wang Mingzhao Ning Yalan Meng Zhaoxing Liu Boli |
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| Abstract: | The in situ coordination of seven salicylaldehyde amino acid Schiff bases in water is investigated. The minimum concentration and pH for coordinating to Zn 2+ and the existing time of the complexes are obtained through the measurement of absorption spectra. And the labeling of 99m Tc is tentatively performed, which indicates the potential of labeling radionuclides by means of the in situ coordination for radiopharmaceutical studies. |
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| Keywords: | salicylaldehyde amino acid Schiff bases Zn 2+ in situ coordination 99m Tc labeling |
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