Emericid,a new polyether antibiotic fromStreptomyces hygroscopicus (DS 24 367) |
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Authors: | L. Ninet F. Benazet H. Depaire J. Florent J. Lunel D. Mancy A. Abraham J. R. Cartier N. De Chezelles C. Godard M. Moreau R. Tissier J. Y. Lallemand |
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Affiliation: | (1) Centre Nicolas Grillet, Rhône-Poulenc Industries, 13, quai Jules Guesde, F-94400 Vitry-sur-Seine, (France);(2) Service de Chimie, Ecole Normale Supérieure, 24 rue Lhomond, F-75005 Paris, (France) |
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Abstract: | Summary Emericid is a new polyether polycyclic ionophore antibiotic excreted byStreptomyces hygroscopicus (DS 24 367). Active in vitro against Gram-positive bacteria, it is ineffective in vivo. At a 0.006–0.02% level in the diet it protects chickens and rabbits against coccidiosis.From a recent paper byN. Otake (Tetrahedron Lett.1970, 4147) emericid and lonomycin would be identical. |
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