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核桃楸皮粗多糖对SMMC-7721和SCG-7901抑制作用研究
引用本文:雷涛,潘艳明,常乐,吴宜艳.核桃楸皮粗多糖对SMMC-7721和SCG-7901抑制作用研究[J].实验室科学,2014(2):30-31,52.
作者姓名:雷涛  潘艳明  常乐  吴宜艳
作者单位:牡丹江医学院药学院,黑龙江牡丹江157011
基金项目:黑龙江省自然科学基金项目(项目编号:D200983),地产核桃楸皮提取物对Hela、H22肿瘤作用及机制研究.
摘    要:目的:探讨核桃楸皮粗多糖对肝癌SMMC-7721和胃癌SCG-7901的抑制作用。方法:应用噻唑蓝比色法和紫外分光光度法,以5-氟尿嘧啶组为阳性对照组,在560nm检测不同剂量的核桃楸多糖溶液的OD值,考察核桃楸皮粗多糖对肿瘤细胞的24h抑制作用。结果:SMMC-7721:IC50=0.60407mg/mL;SCG-7901:IC50=0.23545mg/mL。

关 键 词:核桃楸皮粗多糖  SMMC-  SCG-抑制率

Study on SMMC-7721and SCG-7901 inhibition rates of polysaccharides liquid of juglans mandshurica maxim
LEI Tao,PAN Yah-ruing,CHANG Le,WU Yi-yan.Study on SMMC-7721and SCG-7901 inhibition rates of polysaccharides liquid of juglans mandshurica maxim[J].Laboratory Science,2014(2):30-31,52.
Authors:LEI Tao  PAN Yah-ruing  CHANG Le  WU Yi-yan
Institution:(School of Pharmacy, Mudanjiang Medical College, Mudanjiang 157011, China)
Abstract:Objective: Study on cell SMMC-7721 and SCG-7901 Inhibition rates of Polysaccharides Liquid of Juglans Mandshurica Maxim. Methods: Experimentations detection the OD of Polysaccha- rides Liquid by MTT . Detect the absorbance at 560 nm by ultraviolet spectrophotometer . Results: Experimentations show the better Inhibition rates on cell SMMC-7721 and SCG-7901. (Extraction Liquid) SMMC-7721: IC50=0. 60407mz/ml: SCG-7901. IC50=0. 23545mg/ml.
Keywords:juglans mandshurica maxim  polysaccharides  SMMC-7721  SCG-7901  inhibitionrate
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