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Determination of infarct size in rats with86rubidium
Authors:H Braselmann  Ulrike Osswald  K Wenzelides  E Seidler
Institution:(1) Institute of Pathology, Humboldt-University Berlin, P.O. Box 140, DDR-104 Berlin, (German Democratic Republic)
Abstract:Summary A quick method is presented which allows the determination of infarct sizes within hearts of experimental animals like rats. The method is based on the drop of86Rb uptake in infarcted hearts, and has been compared with infarct sizes determined morphometrically. The standard deviation of this method is low (6.5%) because an internal standard is used (noninfarcted myocard-usually right ventricle tissue-has been used).
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