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Influences of the chemical structure on the activity of new inhibitory compounds of the angiotensin-converting enzyme |
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| Authors: | W -E Siems G Heder K D Jentzsch U Burkhardt S Johne H Kühmstedt K Kottke I Wunderlich P Oehme |
| Institution: | (1) Institute of Drug Research, Academy of Sciences of the GDR, DDR-1136 Berlin, (German Democratic Republic);(2) Institute of Biochemistry of Plants, Academy of Sciences of the GDR, DDR-4010 Halle (Saale), (German Democratic Republic);(3) Section of Pharmacy, Ernst-Moritz-Arndt-University Greifswald, DDR-2200 Greifswald, (German Democratic Republic) |
| Abstract: | Summary The ACE inhibitory activity of some perimidines, chinazolinones and amidinohydrazones is described. Relations were found between the chemical structure and the inhibitory activity on the ACE. |
| Keywords: | Angiotensin-converting enzyme (ACE) new ACE inhibitory compounds perimidines chinazolinones amidinohydrazones structure-activity-relations |
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