Atmungseffekte bei intermittierender elektrischer Reizung der Medulla oblongata zu verschiedenen Zeitpunkten des Atmungszyklus beim Kaninchen

Summary In urethane-anesthetized rabbits the bulbar reticular formation was stimulated with volleys of 120 msec duration at 100 pulses per sec, the pulse duration being 0.5 msec. When shifted along the inspiration, the volleys caused an increasingly stronger inhibition followed by a rebound activation of the inspiratory activity. Towards the end of the inspiration, the volleys stopped the latter phase and shortened the following expiration. When applied during the expiration, the volleys also caused an inhibition and shortened this phase. Results suggest that the stimulus-induced pause of the inspiratory activity delays the activation by the inspiratory centre of the central inhibitory feedback mechanism.

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Unterstützt durch die Freiwillige Akademische Gesellschaft der Stadt Basel und die Sandoz-Stiftung zur Förderung der medizinisch-biologischen Forschung.