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Ultrastructural changes of the luminal plasma membrane of the transitional epithelium of the rat urinary tract in essential fatty acid deficiency
Authors:B Monis  A Eynard  D Lis  F Kalinec
Institution:(1) Instituto de Biología Celular, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Casilla Postal 362, Córdoba, (Argentina)
Abstract:Summary Rats fed an essential fatty acid deficient diet (EFAD) showed a statistically significant decrease in the thickness and ultrastructural asymmetry of the luminal membrane and cytoplasmic vesicles of transitional epithelium of the urinary tract, due to a marked thinning of the peculiar thick luminal leaflet. These changes were reversed by adding EFA to the diet. This indicates that the unusual EM appearance of urothelial membrane depends on its content in EFA.Acknowledgment is due to Mrs.M. G. Iwakawa andN. T. Benítez for technical help and Mr.J. Hiza for animal care.D. Lis andA. Eynard are research fellows of Consejo Nacional de Investigaciones Científicas y Técnicas. Work supported in part by CONICET, Argentina.
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