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Research progress in nonlinear analysis of heart electric activities
作者姓名:NING  Xinbao  BIAN  Chunhua  WANG  Jun  CHEN  Ying
作者单位:State Key Laboratory of Modem Acoustics, Institute for BiomedicalElectronic Engineering, Department of Electronic Science & Engineering, Nanjing University, Nanjing 210093, China
摘    要:1INTRODUCTION THE WORLD IS NONLINEAR,AND THE HUMAN LIFE ACTIVITY IS ALSO NONLINEAR.FROM THE VIEWPOINT OF SYSTEM,HUMAN BEINGS(OR THE OTHER HIGHER ANIMAL)ARE THE MOST COM-PLEX SYSTEM IN THE NATURE.FOR SUCH A PHYSIOLOGICAL SYS-TEM WITH THE UTTERMOST COMPLEXI…

关 键 词:心电图  心率  非线性分析  混沌信号  研究进展
收稿时间:2005-04-19
修稿时间:2005-04-192005-12-23

Research progress in nonlinear analysis of heart electric activities
NING Xinbao BIAN Chunhua WANG Jun CHEN Ying.Research progress in nonlinear analysis of heart electric activities[J].Chinese Science Bulletin,2006,51(4):385-393.
Authors:Xinbao Ning  Chunhua Bian  Jun Wang  Ying Chen
Institution:(1) State Key Laboratory of Modern Acoustics, Institute for Biomedical Electronic Engineering, Department of Electronic Science & Engineering, Nanjing University, Nanjing, 210093, China
Abstract:Nonlinear science research is a hot point in the world. It has deepened our cognition of determinism and randomicity, simplicity and com-plexity, noise and order and it will profoundly influ-ence the progress of the study of natural science, including life science. Life is the most complex nonlinear system and heart is the core of lifecycle system. In the late more than 20 years, nonlinear research on heart electric activities has made much headway. The commonly used parameters are based on chaos and fractal theory, such as correlation dimension, Lyapunov ex-ponent, Kolmogorov entropy and multifractal singu-larity spectrum. This paper summarizes the commonly used methods in the nonlinear study of heart electric signal. Then, considering the shortages of the above tradi-tional nonlinear parameters, we mainly introduce the results on short-term heart rate variability (HRV) signal (500 R-R intervals) and HFECG signal (1-2s). Finally, we point out it is worthwhile to put emphasis on the study of the sensitive nonlinearity parameters of short-term heart electric signal and their dynamic character and clinical effectivity.
Keywords:nonlinear  chaos  fractal  electrocardiogram (ECG)  heart rate variability (HRV)  
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