| 肠型脂肪酸结合蛋白研究进展 |
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| 引用本文： | 王家胜,杨强.肠型脂肪酸结合蛋白研究进展[J].世界科技研究与发展,2012(4):611-612,620. |
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| 作者姓名： | 王家胜 杨强 |
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| 作者单位： | 重庆医科大学附属永川医院普外科,重庆402160 |
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| 摘 要： | 肠型脂肪酸结合蛋白（I-FABP，FABP2）是脂肪酸结合蛋白超家族中的重要成员，主要参与机体对脂肪酸的吸收、转运、以及在细胞器内的再分布及利用。近年研究表明，FABP2与代谢性疾病、炎症性疾病、肠组织缺血损伤等密切相关，不但是肠组织损伤的敏感性标志，而且可以作为炎症严重程度的评价指标，并可能成为某些代谢性疾病的药物治疗靶点。
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| 关 键 词： | 肠型脂肪酸结合蛋白 肠道缺血性疾病 炎症性疾病 代谢性疾病 |
Research Progress in Intestinal-type Fatty Acid Binding Protein |
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| WANG Jiasheng,YANG Qiang.Research Progress in Intestinal-type Fatty Acid Binding Protein[J].World Sci-tech R & D,2012(4):611-612,620. |
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| Authors: | WANG Jiasheng YANG Qiang |
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| Institution: | ( Department of Surgery, Yong Chuan Hospital, Chongqing Medical University, Chongqing 402160) |
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| Abstract: | Intestinal-type fatty acid binding protein （ I-FABP, FABP2 ） is a key member of the FABP super family, participating in the organism＇s absorption, transferring, intracellular redistribution and use of fatty acids. Recent research has demonstrated that FABP2 is closely related with metabolic diseases,inflammatory diseases and ischemic injuries of intestinal tissue. It is not only a sensitive sign of intestinal inju- ries but also a severity evaluation indicator of inflammation. What＇s more, it can probably be a pharmacotherapy target of some metabolic diseases. |
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| Keywords: | FABP2 intestinal isehemic disease inflammatory disease metabolic diseases |
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