Protective and immunostimulating activity of a low dose of cyclophosphamide in the experimental infection of mice with foot-and-mouth disease virus |
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Authors: | E. L. Portiansky W. M. T. DiGirolamo R. P. Laguens |
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Affiliation: | (1) Cátedra de Patología II, Facultad de Ciencias Médicas, Universidad Nacional de La Plata, 1900 La Plata, Argentina |
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Abstract: | ![]() Summary Administration to mice of a low, non-immunosuppressive dose of cyclophosphamide 4 days before infection with foot-and-mouth disease virus decreases viral replication, enhances the immune response against the virus and prevents panceatic damage. |
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Keywords: | Foot-and-mouth disease virus cyclophosphamide pancreatitis immune response |
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