Protective and immunostimulating activity of a low dose of cyclophosphamide in the experimental infection of mice with foot-and-mouth disease virus |
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| Authors: | E L Portiansky W M T DiGirolamo R P Laguens |
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| Institution: | (1) Cátedra de Patología II, Facultad de Ciencias Médicas, Universidad Nacional de La Plata, 1900 La Plata, Argentina |
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| Abstract: | Summary Administration to mice of a low, non-immunosuppressive dose of cyclophosphamide 4 days before infection with foot-and-mouth disease virus decreases viral replication, enhances the immune response against the virus and prevents panceatic damage. |
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| Keywords: | Foot-and-mouth disease virus cyclophosphamide pancreatitis immune response |
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