Zur wirkung hypertoner Lösungen auf die markhaltige Nervenfaser |
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| Authors: | H Meves |
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| Institution: | (1) Physiologisches Institut der Universität des Saarlandes, Homburg Saar, Deutschland |
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| Abstract: | Summary The effect of hypertonic solutions on the action potential of single myelinated nerve fibres is described. Hypertonicity mainly changes the duration of the action potential: Short action potentials obtained in normal Ringer's solution at room temperature are prolonged, long action potentials due to 0.1–1.0 mM NiCl2-Ringer's solution and low temperature are shortened by hypertonicity. The changes in action potential duration are accompanied by small changes in action potential amplitude. In addition, hypertonicity reduces the depolarization produced by 20 mM KCl; inactivation of the sodium-carrying system under cathodal polarization is enhanced.
Die Untersuchungen wurden mit Unterstützung der Deutschen Forschungsgemeinschaft ausgeführt. |
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