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STEC的耐药性监测和分析
引用本文:李咏梅,温凤,王岚,吴决. STEC的耐药性监测和分析[J]. 北华大学学报(自然科学版), 2004, 5(1): 31-33
作者姓名:李咏梅  温凤  王岚  吴决
作者单位:北华大学,医学院,吉林,吉林,132001;长春市儿童医院,吉林,长春,130000
摘    要:目的了解各种标本来源的产志贺样毒素大肠杆菌(STEC)对常用抗生素的敏感性.方法采用WHO推荐的K-B法,进行分鉴定菌株对18种抗生素的药物敏感试验,依照NCCLS判定结果.结果各种来源产志贺样毒素的大肠杆菌共46株,O157型23株,其余为非O157型.全部STEC对复方新诺明耐药,对链霉素耐药率为28.3%(13株),氨苄西林为30.4%(14株),红霉素为69.6%(32株),而且有5株对至少4种以上抗生素产生多重耐药,耐药谱为复方新诺明-链霉素-红霉素-氨苄西林.非O157型STEC耐药菌次为122,而O157型为63.结论非O157型STEC对抗生素可能较易形成耐药性.

关 键 词:STEC  耐药性  监测
文章编号:1009-4822(2004)01-0031-03
修稿时间:2003-09-09

Supervision and Analysis of Antibiotic Resistance of Shiga Toxin-Producing Escherichia coli Isolates
LI Yong-mei,WEN Feng,WANG Lan,WU Jue. Supervision and Analysis of Antibiotic Resistance of Shiga Toxin-Producing Escherichia coli Isolates[J]. Journal of Beihua University(Natural Science), 2004, 5(1): 31-33
Authors:LI Yong-mei  WEN Feng  WANG Lan  WU Jue
Affiliation:LI Yong-mei~1,WEN Feng~2,WANG Lan~2,WU Jue~1
Abstract:Objective To explore the antibiotic susceptibility of Shiga toxin-producing Escherichia coli (STEC) isolates from all kinds of samples.Methods 18 kinds of antibiotic susceptibility was tested by Kirby-Bauyer protocol recommended by WHO.Results There were total 46 strains STEC to produce Shiga-like toxin. All STEC strains resisted to Sulfamethoxazole timethoprim, and the rate of resistant to Ampicillin, Erythromycin and Streptomycin was respectively (30.4%), (69.6%), (28.3%). 5 isolates resisted to multiple antibiotics. The total resistant number of non-O157 strains were 122, O157 were 63.Conclusion Non-O157 STEC strains might be liable to antibiotic resistance.
Keywords:Shiga toxin-producing E.coli  Antibiotic resistance  Supervision
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