| 微波辐射下干介质中酰氨基硫脲及其关环产物合成的研究 |
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| 引用本文： | 张力学,熊静.微波辐射下干介质中酰氨基硫脲及其关环产物合成的研究[J].温州大学学报(自然科学版),2000,21(3):18-19. |
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| 作者姓名： | 张力学 熊静 |
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| 作者单位： | 温州师范学院化学系!温州325003 |
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| 摘 要： | 本文用苯乙酰肼与苯基异硫氰酸酯在微波辐射下以氧化铝为介质进行反应，合成１－苯乙酰基－４－苯基氨基硫脲；然后分别将其在冰醛酸、醋酸汞存在下关环，制得２－苯甲基－５－苯胺基－１，３，４－噻二唑与２－苯甲基－５－苯胺基－１，３，４恶二唑。
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| 关 键 词： | 微波辐射 干介质 酰氨基硫脲 合成 药物 |
Study on Synthesis of Acyl Thiosemicarbazide and Its Ring Closure Products in Dry Media under Microwave Irradiation |
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| Zhang Lixue,Xiong Jing.Study on Synthesis of Acyl Thiosemicarbazide and Its Ring Closure Products in Dry Media under Microwave Irradiation[J].Journal of Wenzhou University Natural Science,2000,21(3):18-19. |
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| Authors: | Zhang Lixue Xiong Jing |
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| Institution: | Department of Chemistry |
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| Abstract: | This paper reports the synthesis of 1 phenylacetyl 4 phenyl thiosemicarbazide from phenylacetyl hydrazine and phenyl isothiocyanate with aluminium oxide as a surpport under microwave irradiation.This thiosemicarbazide was treated under the catalysis of glacier acetic acid,mercuric acetate giving 2 benzyl 5 phenylamino 1,3,4 thiodiazole and 2 benzyl 5 phenylamino 1,3,4 oxadiazole respectively. |
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| Keywords: | microwave irradiation dry media acylthiosemicarbazide thiodiazole oxadiazole synthesis |
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