Alpha-tocopherol: Its inhibition on human platelet aggregation |
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Authors: | J. S. C. Fong |
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Affiliation: | (1) Department of Nephrology, Montreal Children's Hospital, 2300 Tupper Street, H3H 1P3 Montreal, Quebec, Canada |
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Abstract: | Summary Alpha-tocopherol inhibits human platelet aggregation induced by arachidonate sodium, collagen, epinephrine, adenosine diphosphate or thrombin — arachidonate sodium being the most susceptible. The second phase of the biphasic platelet aggregation induced by epinephrine or adenosine diphosphate is preferentially inhibited.This work was supported by the Medical Research Council of Canada, Quebec Medical Council, and a Fraser Scholarship, McGill University. I thank Drs.K. N. Drummond andS. O'Regan for their comments. |
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