Effect of intercalating mutagens on crossing-over inDrosophila melanogaster females |
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| Authors: | N Xamena A Creus R Marcos |
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| Institution: | (1) Departamento de Genética, Facultad de Ciencias, Universidad Autónoma de Barcelona, Bellaterra, (Spain);(2) Present address: Facultad de Veterinaria, UAB, Bellaterra |
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| Abstract: | Summary In order to evaluate the effect of several intercalating compounds on crossing-over inDrosophila melanogaster females, acridine orange, acriflavine, chloroquine, ethidium bromide and quinacrine were fed separately to larvae ofy ct f/+++ genotype. Our results show that acridine orange, acriflavine and ethidium bromide increase significantly the recombination frequency at thect-f region and support the view that, for intercalating agents, there is a relationship between clastogenic activity and female recombination induction. |
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| Keywords: | Drosophila melanogaster intercalating mutagens crossing-over clastogenic activity recombination induction |
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