Über die Ätiologie der Lippen-Kieferspaltformen und Gaumenspalten beim Menschen und im Tierexperiment |
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| Authors: | G Pfeifer Th von Kreybig |
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| Institution: | (1) Nordwestdeutsche Kieferklinik, Chirurgische Abteilung der Universitätsklinik und Poliklinik für Zahn-, Mund-und Kieferkrankheiten, Martinistrasse 52, D-2000 Hamburg 20, Deutschland |
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| Abstract: | Summary Only formhydroxamic acid and its certain derivatives induce in rats cleft-lip and palate (CLP) after treatment during early embryonic developmental phase. Other hydroxamic acids and formamide-derivatives caused different malformations but no CLP. Also unknown in rats in the hereditary CLP. The possible causes of CLP in rats are compared with these in mice and men. |
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