Effect of acetylhomocysteine thiolactone on nucleolar cytology and lipofuscinogenesis in electric lobe neurons |
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Authors: | H E Enesco M A Enesco E Aloj Totaro F A Pisanti |
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Institution: | (1) Department of Biology, Concordia University, 1455 de Maisonneuve Blvd. West, H3G 1M8 Montreal, Quebec, Canada;(2) Department of Ecology, University of Calabria at Cosenza, Arcavacata di Rende, Cosenza, (Italy) |
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Abstract: | Summary Treatment with acetylhomocysteine thiolactone significantly reduces the cellular level of lipofuscin in neurons of the electric lobe ofTorpedo marmorata. At the same time, this drug produces a 45% decrease in nucleolar volume in these neurons, reflecting decreased cellular synthetic activity. |
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Keywords: | Lipofuscin nucleolus nucleolar vacuole acetylhomocysteine thiolactone cythiolone |
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