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In vivo effects ofEscherichia coli endotoxin on sulfobromophthalein clearance in the guinea-pig
Authors:R. Utili  C. O. Abernathy  S. A. Aron  H. J. Zimmerman
Affiliation:(1) Liver Research Unit, Veterans Administration Hospital, 50 Irving Street, N. W., 20422 Washington, D. C., USA;(2) Present address: Clinica delle Malattie Infettive, Facolta di Medicina I, Via Cotugna 1, 80135 Napoli, Italy
Abstract:Summary In vivo studies indicated that the primary effects ofE. coli endotoxin on hepatic clearance of sulfobromophthalein were at the excretory level. Newborns were more sensitive to the LPS than older animals.
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