| 北五味子提取液对小鼠耐缺氧和抗疲劳能力的影响 |
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| 引用本文： | 王文燕,王婧婧,韩振坤,邢晓冬. 北五味子提取液对小鼠耐缺氧和抗疲劳能力的影响[J]. 内蒙古民族大学学报(自然科学版), 2008, 23(6): 668-670 |
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| 作者姓名： | 王文燕 王婧婧 韩振坤 邢晓冬 |
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| 作者单位： | [1]内蒙古民族大学,内蒙古通辽028043 [2]河南科技大学第一附属医院,河南洛阳471003 |
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| 摘 要： | 目的：研究北五味子提取液（SCE）对小鼠耐缺氧和抗疲劳能力的影响．方法：选取健康昆明种小鼠120只，随机分为空白对照组和SCE低、中、高剂量组，每组30只，连续灌胃7d．观察小鼠常压耐缺氧存活时间和负重游泳时间，测定游泳前、游泳10min和游泳后20min血清乳酸含量的变化．结果：SCE能显著增加小鼠常压缺氧存活时间和负重游泳时间，并能显著降低游泳后血清乳酸的增加量．结论：SCE能够明显提高小鼠耐缺氧和抗疲劳的能力．
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| 关 键 词： | 北五味子提取液 小鼠 耐缺氧 抗疲劳 |
Effects of Schisandra Chinensis Baill Extract on Anti- hypoxia and Anti- fatigue in Mice |
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| Affiliation: | WANG Wen -yan , WANG Jing - jing, HAN Zhen - kun, XING Xiao - dong (1. Inner Mongolia University for Nationalities,Tongliao 028043, China; 2. The First Affiliated Hospital, Henan University of Science and Technology,Luoyang 471003 ,China) |
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| Abstract: | Objective： To investigate the effects of Schisandra chinensis baill extract（SCE） on anti - hypoxia and anti -fatigue in mice. Methods： 120 healthy Kunming mice were randomly divided into blank control, high,middle and low dose（SCE） groups,30 mice in each group. Intragastric admin- istration once daily for 7 continuous days. The survival time from hypoxia at ordinary pressure and weight- carrying swimming time for mice were observed. The serum content of lactic acid in mice before swimming,after swimming for 10min and 20rain was determined respectively. Results： SCE could significantly increase the survival time from hypoxia and weight - carrying swimming time in mice. And SCE could significantly decrease the production of serum lactic acid after swinming. Conclusion： SCE can obviously improve the ability of anti - hypoxia and anti - fatigue in mice. |
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| Keywords: | SCE Mouse Anti - hypoxia Anti - fatigue |
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