| DNA编码的模型分析 |
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| 引用本文： | 周康,殷燕芳,李玉华,覃磊.DNA编码的模型分析[J].华中科技大学学报(自然科学版),2007,35(7):67-70. |
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| 作者姓名： | 周康 殷燕芳 李玉华 覃磊 |
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| 作者单位： | 武汉工业学院,数理科学系,湖北,武汉,430023;华中科技大学,控制科学与工程系,湖北,武汉,430074;武汉工业学院,机械系,湖北,武汉,430023;武汉工业学院,数理科学系,湖北,武汉,430023 |
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| 基金项目： | 国家自然科学基金
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湖北省自然科学基金
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湖北省优秀中青年创新团队资助项目
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湖北省社会科学基金
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浙江省自然科学基金 |
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| 摘 要： | 提出了适应DNA计算的DNA编码问题.对等码长的DNA编码问题的数学模型进行分析.以优化码长作为目标,分析了约束条件.以杂交反应为核心将约束条件分为基本约束和控制生化实验的约束,而控制生化实验的约束包含组合约束和热力学约束.控制移动不匹配的下值才能控制杂交反应,由此改进了移动距离.引入窗口距离解决了错配总量和分布的控制问题.
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| 关 键 词： | DNA编码 杂交反应 数学模型 窗口距离 |
| 文章编号： | 1671-4512（2007）07-0067-04 |
| 修稿时间： | 2006-04-26 |
Analysis of DNA encoding by using the model |
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| Zhou Kang,Yin Yanfang,Li Yuhua,Qin Lei.Analysis of DNA encoding by using the model[J].JOURNAL OF HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY.NATURE SCIENCE,2007,35(7):67-70. |
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| Authors: | Zhou Kang Yin Yanfang Li Yuhua Qin Lei |
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| Institution: | 1 Department of Mathematics and Physics; 2 Department of Mechanical Engineering, Wuhan Polytechnic University, Wuhan 430023, China; 3 Departmentof Control Science and Engineering, Huazhong University of Science and Technology, Wuhan 430074, China |
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| Abstract: | The DNA encoding is a pivotal step of DNA computing. DNA encoding problem fitting to DNA computing was put forward. At the same time, we study mathematics model of equal-length DNA encoding. First we put forward optimizing length of encoding as objective function. Then we study restriction conditions, which are foundation restriction conditions and controlling bio-chemistry experiment restriction conditions for hybridization. And the second restriction conditions contain combination restriction conditions and thermodynamic restriction conditions. Because only by controlling lower limit value of moving non-matching can control hybridization, moving distance is put ringt. In combination restriction conditions, we bring forward window distance in order to control number and distributing of error-match. |
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| Keywords: | DNA encoding hybridization mathematics model window distance |
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