Comparison of chemiluminescence and absorptiometry in enzyme immunoassays for protein quantification

Summary The use of chemiluminescence in competitive binding assays for human serum albumin human alphafetoprotein and human immunoglobulin G and in double antibody sandwich enzyme immunoassays for cytomegalovirus and herpes simplex virus increased the sensitivity of the detection of antigen or antibody 16- to 95-fold above that obtained by conventional absorptiometric methods.Acknowledgments. This study was supported by Public Health Service research training grant T-32-AD 07018 from the Institute of Allergy and Infectious Diseases. To whom reprint requests should be addressed