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Inhibitory effect of methionine- and leucine-enkephalin on contractions of the guinea-pig ileum elicited by PGE1
Authors:R Jaques
Institution:(1) Research Department, Pharmaceuticals Division, CIBA-GEIGY Limited, CH-4002 Basel, (Switzerland)
Abstract:Summary Methionine-enkephalin and leucine-enkephalin (m-enk and l-enk) have been shown to antagonize contractions of the isolated guinea-pig intestine elicited by PGE1. The inhibitory effect of these 2 pentapeptides is abolished by naloxone.
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