D-aspartate oxidase activity and D-aspartate content in a mutant mouse strain lacking D-amino acid oxidase |
| |
| Authors: | H Nagasaki R Yamada R Konno Y Yasumura A Iwashima |
| |
| Institution: | Department of Biochemistry, Kyoto Prefectural University of Medicine, Japan. |
| |
| Abstract: | A mutant mouse strain ddY/DAO- lacks D-amino acid oxidase activity and accumulates free neutral D-amino acids in its tissues. In this study, D-aspartate oxidase activity and D-aspartate content in the tissues of these mutant mice were compared with those of normal mice. No significant difference was observed, indicating that the metabolism of acidic D-amino acids was unaffected in the mutant. |
| |
| Keywords: | |
|
|
