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A new semisynthetic ergot peptide alkaloid: DCN 203-922 |
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| Authors: | R K A Giger H R Loosli M D Walkinshaw B J Clark J M Vigouret |
| Institution: | (1) Preclinical Research, Sandoz Ltd., CH-4002 Basel, (Switzerland) |
| Abstract: | Summary We report the synthesis, stereochemistry and preliminary pharmacological evaluation of DCN 203-922, a novel ergot alkaloid of the cyclol type, which contains in its peptide moiety the uncommon amino acid L-allo-isoleucine.Part of this paper was reported by this author at the Herbstversammlung der Schweizerischen Chemischen Gesellschaft, Bern, in October 1986. |
| Keywords: | DCN 203-922 DH- |
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