房颤R-R间期关联性比正常窦性心律弱

利用概率密度函数(PDF)法、相空间图法和互信息函数法分析了正常窦性心律(NSR)及房颤(AF)R-R间期.延时较小时,NSR R-R间期PDF不对称分布,延时较大时,PDF满足高斯分布,证明邻近NSR R-R间期关联性强;而AF R-R间期PDF为高斯分布,且不同延时PDF曲线重合,证明邻近AF R-R间期关联性弱.相空间图和互信息法也得到了相同的结论.AF R-R间期关联性较NSR R-R间期弱是房颤病理信息的反映,这有可能成为新的诊断手段.

Less correlation between R-R intervals of atrial fibrillation than that of normal sinus rhythm

Probability density function(PDF),phase space diagram,and mutual information function are utilized to analyze normal sinus rhythm(NSR) and atrial fibrillation(AF) R-R intervals.It is found that for NSR R-R intervals,PDF is not symmetrically distributed when time delay is small,while PDF satisfies Gauss distribution when time delay is big enough,demonstrating that the correlation between neighboring NSR R-R intervals is strong.For AF R-R intervals,PDF curves are of Gaussian distribution and the curves are nearly the same for different time delays,demonstrating that the correlation between neighboring AF R-R intervals is weak.The same conclusion is drawn by phase space diagram and mutual information method.The less correlation between RR intervals of AF than that of NSR is the reflection of AF pathological information,which may be developed as a new diagnostic method.