Altered brain cyclic AMP-responses in rats reared in enriched or impoverished environments |
| |
| Authors: | R K Dismukes J W Daly |
| |
| Institution: | (1) National Institute of Arthritis, Metabolism and Digestive Diseases, National Institutes of Health, 20014 Bethesda, Maryland, USA;(2) Present address: Medical Faculty, Department of Pharmacology, Free University, Van der Boechorststraat 7, Z II Amsterdam, The Netherlands |
| |
| Abstract: | Summary The accumulation of radioactive cyclic AMP elicited by various neurohormones has been examined in adenine-labeled telencephalon slices from rats raised in enriched or impoverished environments. Basal levels of cyclic AMP and responses of the brain slice cyclic AMP-generating systems to norepinephrine, isoproterenol and adenosine did not differe between the two group of rats, while responses to prostaglandin E1 were significantly greater with the impoverished group and responses to histamine appeared to be greater with the enriched group. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
