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fMRI time series analysis based on stationary wavelet and spectrum analysis
作者姓名:ZHI Lianhe  ZHAO Xi  SHAN Baoci  PENG Silong  YAN Qiang  YUAN Xiuli  TANG Xiaowei
作者单位:1. Key Laboratory of Nuclear Analysis Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China; 2. Graduate School of Chinese Academy of Sciences, Beijing 100049, China; 3. Department of Physics, Zhoukou Normal University, Zhoukou 466100, China; 4. Research Imaging Center, University of Texas Health Science Center, San Antonio, Texas 78229, USA; 5. National ASIC Design and Engineering Center, Institute of Automation, Chinese Academy of Sciences, Beijing 100049, China; 6. Department of Physics, Zhejiang University, Hangzhou 310027, China
基金项目:国家自然科学基金;国家重点基础研究发展计划(973计划)
摘    要:The low signal to noise ratio (SNR) of functional MRI (fMRI) prefers more sensitive data analysis methods. Based on stationary wavelet transform and spectrum analysis, a new method with high detective sensitivity was developed for analyzing fMRI time series, which does not require any prior assumption of the characteristics of noises. In the proposed method, every component of fMRI time series in the different time-frequency scales of stationary wavelet transform was discerned by the spectrum analysis, then the components from noises were removed using the stationary wavelet transform, finally the components of real brain activation were detected by cross-correlation analysis. The results obtained from both simulated and in vivo visual experiments illustrated that the proposed method has much higher sensitivity than the traditional cross-correlation method.

关 键 词:fMRI,  stationary  wavelet  transform,  spectrum  analysis,  data  analysis

fMRI time series analysis based on stationary wavelet and spectrum analysis
ZHI Lianhe,ZHAO Xi,SHAN Baoci,PENG Silong,YAN Qiang,YUAN Xiuli,TANG Xiaowei.fMRI time series analysis based on stationary wavelet and spectrum analysis[J].Progress in Natural Science,2006,16(11):1171-1176.
Authors:ZHI Lianhe  ZHAO Xia  SHAN Baoci  PENG Silong  YAN Qiang  YUAN Xiuli  TANG Xiaowei
Institution:1. Key Laboratory of Nuclear Analysis Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049,China;Graduate School of Chinese Academy of Sciences, Beijing 100049, China;Department of Physics, Zhoukou Normal University, Zhoukou 466100,China
2. Research Imaging Center, University of Texas Health Science Center, San Antonio, Texas 78229,USA
3. Key Laboratory of Nuclear Analysis Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049,China
4. National ASIC Design and Engineering Center, Institute of Automation, Chinese Academy of Sciences, Beijing 100049, China
5. Key Laboratory of Nuclear Analysis Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049,China;Department of Physics, Zhejiang University, Hangzhou 310027, China
Abstract:The low signal to noise ratio (SNR) of functional MRI (fMRI) prefers more sensitive data analysis methods. Based on stationary wavelet transform and spectrum analysis, a new method with high detective sensitivity was developed for analyzing fMRI time series, which does not require any prior assumption of the characteristics of noises. In the proposed method, every component of fMRI time series in the different time-frequency scales of stationary wavelet transform was discerned by the spectrum analysis, then the components from noises were removed using the stationary wavelet transform, finally the components of real brain activation were detected by cross-correlation analysis. The results obtained from both simulated and in vivo visual experiments illustrated that the proposed method has much higher sensitivity than the traditional cross-correlation method.
Keywords:fMRI  stationary wavelet transform  spectrum analysis  data analysis
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