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慢性萎缩性胃炎动物模型的复制
引用本文:张淑芹,赵林山,郑继奎,杨永良,郭立波.慢性萎缩性胃炎动物模型的复制[J].哈尔滨师范大学自然科学学报,2001,17(6):81-83.
作者姓名:张淑芹  赵林山  郑继奎  杨永良  郭立波
作者单位:1. 哈尔滨医科大学
2. 哈尔滨师范大学
摘    要:本实验采用两种方法复制慢性萎缩性胃炎动物模型:一是水杨酸钠小剂量,长时间灌胃加饥饱失常,劳倦伤脾法;二是注射佐剂抗原引起自身免疫法,经病理检察,两种方法均复制出典型的慢性萎缩性胃炎动物西模型,可见,动物模型的复制方法不是唯一的,采用不同的方法可以复制出相同的动物模型。

关 键 词:慢性萎缩性胃炎  Wistar大鼠  动物模型  发病机制  劳倦伤脾法  自身免疫法
修稿时间:2001年11月2日

REPRODUCING OF ANIMAL MODEL ON THE CHRONIC ATROPHIC GASTRITIS
Zhang Shuqin,Zhao LinshanZheng Jikui,Yang Yongliang,Guo,Libo.REPRODUCING OF ANIMAL MODEL ON THE CHRONIC ATROPHIC GASTRITIS[J].Natural Science Journal of Harbin Normal University,2001,17(6):81-83.
Authors:Zhang Shuqin  Zhao LinshanZheng Jikui  Yang Yongliang  Guo  Libo
Institution:Zhang Shuqin Zhao LinshanZheng Jikui Yang Yongliang Guo Libo(Harbin Medical University)(Harbin Normal University)
Abstract:In this paper,animal model of the chronic atrophic gastritis is reproduced by two methods.One method is that every wistar rat's stomach is perfused with small does sodium salicylate for a long time,meantime added with overstrain and impairment of the spleen.The other is that Wistar rats are injected with adjuvant antigen to lead to auto-immune method.These methods all can duplicate the typical chronic atrophic gastritis.So we concluded that the different method could reproduce the same animal model.
Keywords:Chronic atrophic gastritis  Wistar rat  Animal model
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