毛巾织物“斜坡”织疵形成机理及其克服措施

本文对毛巾织物织口后移、毛圈间距进行了定量分析,阐明了毛巾织物“斜坡”织疵产生的主要原因是两条毛巾之间因不同打纬动程之差形成的剪口大小与织一个毛圈织口的后移量不能相等。最后提出了改第一块平布稍短打纬平布为长打纬平布、级完第一块平布开始织毛圈时使卷取机构停卷二到三纬的措施。实践证明,效果良好。     

Structural and expressional analysis of a cDNA that expresses predominantly in rice stamens

The development of stamen is an important stage during the sexual reproduction in higher plants. Studying the genes that predominantly or even specifically expressed in stamens will aid in undestanding the molecular mechanism of stamen development. The structure of a rice CHS-like gene (D5) which predominantly expressed in anthers has been analysised, showing high structural similarity with two other anther-specific genes (A1 and BA42) fromBrassica napus. Northern analysis also reveals that the three genes share a similar expression pattern and that the expression of D5 may relate to the early development of pollens. It is concluded that D5, A1 and BA42 represent a group of diverged CHS-like genes which are related to stamen development.     

Cyclophosphamide-impaired regulation of hepatic heme metabolism

Summary Im male rats hepatic cytochromes b₅ and P-450 were reduced at different times after treatment with cyclophosphamide (CP) (200 mg/kg i.p. for 3 days). In contrast, microsomal heme did not change until 48 h after the last dose of CP, leading to accumulation of heme in a non-cytochromal form. Parallel to the above changes the heme metabolism showed derangement: -aminolaevulinate synthase, the rate-limiting enzyme in heme synthesis, was depressed and heme oxygenase, the enzyme which catalyzes the oxidative degradation of heme, was increased.     

不同动物小肠肌间神经丛内NOS神经元分布的比较

采用NADPH-黄递酶组织化学法对草鱼、牛蛙、家鸡和大鼠小肠肌间神经丛内NOS阳性神经元的分布进行了比较研究．结果表明，NOS阳性产物在草鱼肌间神经丛中未见分布，而在其它几类动物中阳性反应明显．但在不同动物NOS阳性神经元的形态、分布、密度及神经纤维的分布存在差异．在牛蛙、家鸡和大鼠的小肠肌间神经丛中，NOS阳性神经元的分布从分散到集中，形态呈现由不规则形到规则形再到不规则形的复杂变化；神经节从无到有，神经网络由不发达趋于发达；而在每种动物中，NOS阳性神经元的密度沿肠道由前向后基本呈上升趋势，这种节段性的差异牛蛙极显著，家鸡和大鼠则不甚显著．实验结果提示，随着动物的进化，一氧化氮能神经元在肠肌间神经丛中的分布也更加复杂而有序，从而使胃肠道的调节更加精确．     

美容毛巾的开发试织

探讨了用粘胶无捻长丝作毛经的美容毛巾的开发，并与普通毛巾、无捻棉纱毛巾的作了测试比较。实验表明，粘胶毛巾优于无捻棉纱毛巾，符合作为美容毛巾的基本要求。     

智能混合动力汽车经济性自适应巡航控制策略研究

针对智能混合动力汽车自适应巡航过程中的能量控制策略问题,结合模型预测控制在处理多目标、多约束优化问题方面的优势和粒子群算法运算量小、收敛快的特点,将粒子群算法作为模型预测控制的滚动优化方法,构造基于模型预测控制的粒子群算法.仿真结果表明,文中算法能够使绝大部分工况点落在较低燃油消耗率区域,只有少部分工况点落在非经济区域,虽然多消耗了1.06%的燃油,但在运算速度上却获得了60.3%的提升.     

汽车自适应巡航系统中电子节气门的精确控制

在改装的捷达GTX轿车上研究ACC系统中电子节气门的控制策略.在控制方法中综合应用了多种PID算法,针对直流力矩电机机械特性对控制策略进行了优化,通过单片机的输出比较通道产生PWM以控制电机.通过实验台和实车试验,证明基于该控制策略开发电子节气门控制器的控制效果良好.     

表达长喙田菁SrPCS4烟草的获得及Cd抗性研究

植物螯合肽(phytochelatins,PCs)在植物解除重金属的毒性方面具有重要作用,是以谷胱甘肽为底物,在植物螯肽合成酶(phytochelatin synthase,PCS)催化下合成的.作者已经克隆得到的长喙田菁(Sesba-nia rostrata)植物螯合肽合成酶SrPCS4 cDNA长为1035 bp,其ORF编码177个氨基酸,以pHANNIBAL及pART27为基础,构建了CaMV35S启动子驱动的SrPCS4基因植物表达载体pAM25,采用电击转化方法将pAM25导入根癌农杆菌EHA105,并通过改良叶盘转化方法用该菌株对烟草进行了转化,对转基因烟草进行了PCR与northern-blot检测,研究结果表明得到了表达该基因的烟草,但表达该基因的烟草不能够提高对Cd的抗性.     

Sugar-mimicking glycosidase inhibitors: bioactivity and application

A large number of compounds mimicking the structures of monosaccharides or oligosaccharides have been discovered from natural sources. Such sugar mimics inhibit carbohydrate-degrading enzymes because of a structural resemblance to the sugar moiety of the natural substrate. Carbohydrate-degrading enzymes are involved in a wide range of important biological processes, such as intestinal digestion, posttranslational processing of the sugar chain of glycoproteins, their quality control mechanisms, lysosomal catabolism of glycoconjugates, and some viral infections. It has now been realized that inhibitors of the enzymes have enormous therapeutic potential in diabetes and lysosomal storage disorders. In this review, the general bioactivity, current applications, and the prospects for new therapeutic applications are described. Received 27 August 2008; received after revision 08 November 2008; accepted 03 December 2008     

Glycogen synthase kinase 3β and Alzheimer’s disease: pathophysiological and therapeutic significance

Alzheimer’s disease (AD) is a neurodegenerative disorder associated with cognitive and behavioral dysfunction and is the leading cause of dementia in the elderly. Several studies have implicated molecular and cellular signaling cascades involving the serine-threonine kinase, glycogen synthase kinase β(GSK-3β) in the pathogenesis of AD. GSK-3β may play an important role in the formation of neurofibrillary tangles and senile plaques, the two classical pathological hallmarks of AD. In this review, we discuss the interaction between GSK-3β and several key molecules involved in AD, including the presenilins, amyloid precursor protein, tau, and β-amyloid. We identify the signal transduction pathways involved in the pathogenesis of AD, including Wnt, Notch, and the PI3 kinase/Akt pathway. These may be potential therapeutic targets in AD. Received 19 December 2005; received after revision 24 January 2006; accepted 6 February 2006